Polyethylene propylene glycol, abbreviated as PEPPG, is a multifunctional polymer synthesized through specific chemical reactions between polyethylene glycol (PEG) and polypropylene glycol (PPG). This compound combines the unique properties of PEG and PPG, such as good water solubility, chemical stability, biocompatibility, and low toxicity, making PEPPG widely used in fields such as medicine, maquillage, food additives, and industrial applications. The polyethylene and polypropylene segments in its structure endow it with unique rheological and viscosity regulation capabilities, making PEPPG a key component in various industrial formulations.
This compound is a colorless to yellow transparent oily liquid with a molecular weight of 102.13. In addition, it can dissolve with organic solvents such as cold water, ethanol, acetone, carbon tetrachloride, benzene, and ether.
Technical Parameter of Polyethylene-Polypropylene Glycol
Model | Average molecular weight | Viscosity (25 ℃ CPS) |
L31 | 1100 | 200 |
L35 | 1900 | 320 |
F38 | 5000 | - |
L42 | 1630 | 250 |
L43 | 1850 | 310 |
L44 | 2200 | 400 |
L45 | 2400 | - |
L61 | 2000 | 285 |
L62 | 2500 | 400 |
L63 | 2650 | 475 |
L64 | 2900 | 500 |
P65 | 2500 | - |
F68 | 8350 | - |
Increasing the solubility of drugs: Polypropylene propylene glycol can help increase the solubility of certain drugs in water, thereby improving their bioavailability and efficacy.
As emulsifier and stabilizer: Polyphyllene polypropylene glycol is commonly used as emulsifier and stabilizer in the pharmaceutical industry, which can help to prepare stable lotion or suspensions of drugs.
Sustained-release material: Polystyrene polypropylene glycol can also be used as a sustained-release material to achieve long-term therapeutic effects by controlling the release rate of drugs.
Application in ophthalmic administration: Polypropylene propylene glycol also has a wide range of applications in ophthalmology administration, and can be used as a formula ingredient for eye drops or ointments to help drugs exert therapeutic effects in the eyes.
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Payment Term
L/C, T/T, Western Union, Paypal, Credit Card etc.
Shipment Term
By sea, by air, by express, as customers request.
Storage Conditions:
Sealed storage: Polyethylene propylene glycol should be stored in a sealed container to prevent emerge to air, thereby avoiding oxidation and moisture absorption.
Avoid high temperatures: Polyethylene propylene glycol should be stored in a dry, cool, and ventilated room, away from sources of fire and heat, to prevent it from deteriorating due to heat.
Avoid contact with chemicals: Polyethylene propylene glycol should avoid contact with acids, bases, and other chemicals to prevent chemical reactions from occurring.
Regular inspection: Regularly inspect the quality and condition of the polyethylene propylene glycol. If any abnormalities or performance degradation are found, timely measures should be taken.
Q1
How does it affect the mechanical properties and thermal stability of polymer materials when preparing them?
Re:Polyethylene propylene glycol can be used as a plasticizer or chain extender in the preparation of polymer materials, significantly affecting the mechanical properties and thermal stability of the material. By introducing a polyethylene propylene glycol, the flexibility of polymer chains can be increased, the glass transition temperature of materials can be reduced, and the toughness and ductility of materials can be improved. However, excessive addition may lead to a decrease in the strength of the material. In addition, the introduction of polyethylene propylene glycol may also affect the thermal stability of the material, as it may undergo oxidation or decomposition at high temperatures, thereby affecting the long-term thermal performance of the material.
Q2
When used as a solvent or diluent, what is the solubility and volatility of polyethylene propylene glycol?
Re:Polypropylene glycol, as a solvent or diluent, has excellent solubility, especially for polar compounds and polymers. It can effectively reduce the viscosity of the solution, improve the dispersion and solubility of the substance. In addition, the volatility of polyethylene propylene glycol is low, which means it is not easily volatile at room temperature, making it perform well in applications that require long-term stability.
Q3
How to adjust the concentration of polyethylene propylene glycol to optimize its performance in specific applications?
Re:Adjusting the concentration of polyethylene propylene glycol is a key step in optimizing its performance. The specific concentration adjustment depends on the applied field and requirements. For example, in coatings and inks, increasing the concentration of polyethylene propylene glycol can improve wetting and leveling properties, but excessive addition may lead to prolonged drying time or decreased water resistance. When preparing polymer materials, an appropriate concentration can balance the mechanical and processing properties of the material.
Q4
How to evaluate the biocompatibility and safety of polyethylene propylene glycol?
Re:The biocompatibility and safety assessment of polyethylene propylene glycol typically involves multiple aspects. Firstly, it is necessary to conduct in vitro toxicity tests, such as cytotoxicity tests and skin irritation tests, to evaluate their impact on biological tissues. Secondly, in vivo toxicity experiments, such as acute toxicity experiments and chronic toxicity experiments, are also necessary to evaluate their long-term effects in the organism. In addition, it is necessary to evaluate the biodegradability and ecotoxicity of polyethylene polypropylene glycol.
Q5
What are the requirements for the long-term stability and storage conditions of polyethylene propylene glycol?
Re:The long-term stability of polyethylene propylene glycol is the key to ensuring its neutral performance stability in practical applications. To ensure its long-term stability, storage conditions are crucial. Polypropylene propylene glycol should be stored in a dry, cool, and well ventilated place, avoiding direct sunlight and high temperatures. In addition, it is necessary to avoid contact with chemical substances such as acids and bases to prevent chemical reactions from occurring and causing deterioration. Storage containers should be well sealed to prevent the entry of oxygen and moisture. During the storage process, the quality and performance of polyethylene propylene glycol should be regularly checked and tested to ensure its stability and effectiveness.
Other Names | Pluronic |
CAS No. | 9005-67-8 |
Compound Formula | HO(C2H4O)a(C3H6O)b(C2H4O)cH |
Molecular Weight | N/A |
Appearance | Colorless transparent liquid to white paste to white solid |
Melting Point | N/A |
Boiling Point | N/A |
Density | N/A |
Solubility in H2O | N/A |
Exact Mass | N/A |
Polyethylene-polypropylene glycol Health & Safety Information | |
Signal Word | N/A |
Hazard Statements | Irritation to skin and eyes. |
Hazard Codes | N/A |
Risk Codes | N/A |
Safety Statements | N/A |
Transport Information | N/A |