Is Silicon Nitride Harmful to Humans?
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Is Silicon Nitride Harmful to Humans?

2022-11-08 10:15:38  News

Silicon nitride has incredible strength and durability. Its high dielectric constant allows it to be used for several applications, including biomedical implants. Silicon nitride is ideal for orthopedic implants because it has the same hardness, stiffness, and strength as metal. However, it is much less brittle. It is bioactive and can be used for joint replacements, spine implants, and other orthopedic applications.


There are many forms of silicon nitride, including metals and powders. It is commercially available in large quantities but can also be customized for industrial and research applications. Silicon nitride can be found in high-end bearings for gas and diesel engines, computer disk drives, and motorsports equipment. In addition, it is used in rocket nozzles and thrusters.


Silicon nitride can also release NH_3, which can interact with H_2O and form NH_4+ ions. However, it is unclear whether silicon nitride is safe or effective for personal protective equipment use. The adverse biological effects of silicon nitride depend on its particle size, surface composition, donor variation, and donor variation. These variables influence the platform used for the biological evaluation of silicon nitride, which was evaluated through cytotoxicity, inflammatory cytokine release, and oxidative stress.


The chemical composition of silicon nitride can be measured with XPS. By measuring the concentration of silicon, O, and Cr, the XPS method can determine the ratio of the various components. For example, a high concentration of Si and Nb can be used to identify the presence of Nb or Co.


The study found that silicon nitride has relatively good adhesion and mechanical properties. The coating without the interlayer shows decreased adhesion and greater delamination. The interlayer can also reduce delamination during adhesion testing. Additionally, differences in composition between the top and bottom layers did not affect the surface roughness or adhesion properties.


The dissolution behavior of the material was also evaluated. The samples were placed in DMEM cell culture media containing 5% CO2 and 1% penicillin/streptomycin. In addition, FBS was not added to the dissolution medium to avoid contamination and improve ionic compounds' extraction. The dissolution container used in the experiments had eight-mm-diameter wells and Viton O-rings at the edges to prevent leakage. The specimen surface area to cell culture medium volume ratio was 0.47 cm2 mL-1. After the containers had been autoclaved, the samples were immersed in 70% Isopropanol for ten minutes.

A comparison of the pure extract and its ion release was made. The ion release is lower if the coating has a higher Cr content. This means that silicon nitride is more stable and reduces the release of ions.


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